An organism that reproduces asexually would have a different karyotype from a human because it would not have any sex chromosomes. In humans, sex chromosomes determine the sex of an individual and contain genes for sexual development. Asexually reproducing organisms, however, do not have sex chromosomes and instead reproduce through processes like mitosis or fragmentation, where an exact copy of the parent's genetic material is passed on to the offspring. As a result, their karyotype would not include the X and Y chromosomes typically associated with human males and females.