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  • Pyruvate Oxidation: Products, Role in Cellular Respiration
    The products of pyruvate oxidation are:

    * 1 molecule of NADH: This is a reduced electron carrier that will be used in the electron transport chain to generate ATP.

    * 1 molecule of CO2: This is a waste product that is exhaled from the body.

    * 1 molecule of acetyl-CoA: This is the key product that enters the Krebs cycle (also known as the citric acid cycle).

    Here's a summary of the reaction:

    Pyruvate + NAD+ + CoA → Acetyl-CoA + NADH + CO2

    Important Notes:

    * Pyruvate oxidation occurs in the mitochondrial matrix of eukaryotic cells.

    * This process is a crucial step in cellular respiration, linking glycolysis (which occurs in the cytoplasm) to the Krebs cycle.

    * The acetyl-CoA produced will be used to generate ATP through the Krebs cycle and oxidative phosphorylation.

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