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  • Citric Acid Formation: The First Step of the Citric Acid Cycle
    When oxaloacetic acid (OAA) and Acetyl-CoA combine, they form citric acid, also known as citrate. This reaction is the first step of the citric acid cycle (also known as the Krebs cycle).

    Here's a simplified breakdown:

    * Oxaloacetic acid (OAA) is a four-carbon molecule.

    * Acetyl-CoA is a two-carbon molecule carrying an acetyl group.

    * Citric acid is a six-carbon molecule formed by the combination of OAA and the acetyl group from Acetyl-CoA.

    The enzyme citrate synthase catalyzes this reaction, which is an irreversible step in the citric acid cycle.

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