Methanol (CH3OH) and ammonia (NH3) are both polar solvents, and they can be mixed in any proportion. The mixture of methanol and ammonia is often used as a solvent for various chemical reactions. For example, the mixture of methanol and ammonia is used as a solvent for the synthesis of organic compounds, such as amino acids and peptides.

Additionally, the mixture of methanol and ammonia is also used as a solvent for the purification of proteins and nucleic acids.