When you take a drug, it enters your body through various routes, such as swallowing, injection, inhalation, or absorption through the skin or mucous membranes. From there, the drug is distributed throughout your body by your bloodstream.

The liver and kidneys are primarily responsible for filtering and removing drugs from the body. The liver breaks down the drug into metabolites, which are either inactive or less active than the original drug. The kidneys then filter the metabolites from the bloodstream and excrete them in the urine.

Some drugs can remain in the body for a long time, especially if they are fat-soluble, bind strongly to tissues, or are excreted slowly by the kidneys. These drugs can accumulate in the body and cause side effects or toxicity. For this reason, it is important to take drugs exactly as prescribed by your doctor and to be aware of any potential drug interactions