The first enzyme to mix with food in the digestive system is salivary amylase.

Here's why:

* Location: Salivary amylase is produced by the salivary glands in your mouth.

* Action: It starts breaking down carbohydrates (starches) in your food into simpler sugars even before the food reaches your stomach.

While other enzymes are involved in digestion, salivary amylase is the first to act on the food we consume.