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  • Understanding Multiple Alleles: The ABO Blood Group Example
    A classic example of a single gene with multiple alleles is the ABO blood group system in humans.

    Here's how it works:

    * Gene: The ABO blood group system is determined by a single gene called ABO, located on chromosome 9.

    * Alleles: This gene has three common alleles:

    * I^A: Codes for the production of the A antigen on red blood cells.

    * I^B: Codes for the production of the B antigen on red blood cells.

    * i: Codes for the production of neither A nor B antigens.

    * Phenotypes: These alleles combine to create four different blood types:

    * Type A: I^A I^A or I^A i

    * Type B: I^B I^B or I^B i

    * Type AB: I^A I^B

    * Type O: i i

    In summary, a single gene (ABO) with three alleles (I^A, I^B, and i) determines the four different ABO blood types.

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