The process in which a strand of DNA is used as a template for the manufacture of pre-mRNA is called transcription.

Here's a breakdown:

* DNA: The genetic blueprint of an organism, containing the instructions for building proteins.

* pre-mRNA: A precursor molecule to mRNA, containing introns that need to be removed before translation.

* Transcription: The process where the genetic information encoded in DNA is copied into a molecule of pre-mRNA.

During transcription, an enzyme called RNA polymerase reads the DNA sequence and uses it to build a complementary pre-mRNA molecule. This pre-mRNA molecule then undergoes further processing to become mature mRNA, which can then be translated into a protein.