The largest organelle in a eukaryotic cell is the nucleus. DNA is located within the nucleus, specifically within structures called chromosomes.

Here's a breakdown:

* Eukaryotic Cells: These cells have a membrane-bound nucleus that contains their genetic material.

* Nucleus: The control center of the cell, containing the cell's DNA.

* Chromosomes: Structures made of tightly coiled DNA and proteins. DNA is organized into genes, which carry the instructions for building and maintaining the cell.

So, to answer your question directly: DNA is located in the nucleus, within the chromosomes, of eukaryotic cells.