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  • Mitosis Anaphase: When Sister Chromatids Separate - A Detailed Explanation
    Sister chromatids separate during anaphase of mitosis.

    Here's a breakdown of why:

    * Prophase: Chromosomes condense and become visible.

    * Metaphase: Chromosomes line up at the center of the cell (metaphase plate).

    * Anaphase: The centromeres of each chromosome split, and the sister chromatids are pulled apart by spindle fibers towards opposite poles of the cell.

    * Telophase: The chromosomes reach the poles and begin to uncoil. The nuclear envelope reforms around each set of chromosomes, and the cell divides (cytokinesis).

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