• Home
  • Chemistry
  • Astronomy
  • Energy
  • Nature
  • Biology
  • Physics
  • Electronics
  • Calculating Heterozygote Frequency (Bb) with Given Allele Frequency
    The allele frequency doesn't directly tell you the genotypic frequency of heterozygotes. Here's how to calculate it:

    Understanding the Basics

    * Allele Frequency: The proportion of a specific allele in a population. You're given that the frequency of allele B is 0.7. This means the frequency of allele b is 0.3 (since allele frequencies must add up to 1).

    * Genotype Frequency: The proportion of individuals in a population with a specific genotype (like Bb).

    Hardy-Weinberg Equilibrium

    To calculate genotypic frequencies, we use the Hardy-Weinberg Principle, which describes the relationship between allele and genotype frequencies in a population that's not evolving. The key equations are:

    * p + q = 1 (where p is the frequency of allele B, and q is the frequency of allele b)

    * p² + 2pq + q² = 1 (where p² is the frequency of BB, 2pq is the frequency of Bb, and q² is the frequency of bb)

    Calculation

    1. Find the frequency of Bb (2pq):

    * p = 0.7

    * q = 0.3

    * 2pq = 2 * 0.7 * 0.3 = 0.42

    Answer: The genotypic frequency of heterozygotes (Bb) is 0.42, or 42%.

    Science Discoveries © www.scienceaq.com