* To the north: Lynx (a faint constellation), Ursa Major (the Big Dipper), and Gemini (the Twins).
* To the south: Hydra (the Water Snake), Leo (the Lion), and Sextans (the Sextant).
* To the east: Leo
* To the west: Gemini
Cancer is a relatively faint constellation, making it a bit harder to find amongst its brighter neighbors.