In scientific inquiry, making an observation typically leads to a question.

Here's why:

* Observations spark curiosity: When we observe something interesting or unexpected, it naturally leads us to wonder "why?" or "how?"

* Questions drive investigation: These questions become the foundation for further scientific investigation. We want to understand the observed phenomenon, and that leads us to design experiments, gather data, and analyze it.

Here's an example:

* Observation: You notice that plants on the sunny side of your house grow taller than those on the shady side.

* Question: Why do plants grow taller in sunlight?

This question would then lead you to investigate the role of sunlight in plant growth through experimentation.

So, in scientific inquiry, observation is often the starting point, leading to a question that propels the research process forward.