While bald eagles are known to have diverse diets, there is no evidence to support that they significantly prey on prairie dogs in the Great Plains or any other region. Bald eagles primarily feed on fish, waterfowl, and other aquatic prey, and their diet composition varies based on habitat and available food resources. While bald eagles may occasionally consume small mammals, such as rodents, as opportunistic feeders, prairie dogs are not typically part of their regular diet or a primary food source.