Mesoamerica is located in Central America and southern Mexico. It stretches from southern Mexico in the north, encompassing the modern-day countries of Guatemala, Belize, El Salvador, Honduras, Nicaragua, and northern Costa Rica.

Here's a breakdown:

* North: Mexico

* South: Northern Costa Rica

* East: Caribbean Sea

* West: Pacific Ocean

This region is referred to as Mesoamerica due to its historical and cultural significance, as it was home to several ancient civilizations like the Maya, Aztec, and Olmec.