* Organelles and Energy Release: The organelle responsible for releasing energy from glucose is the mitochondrion.

* Cellular Respiration: Mitochondria are the powerhouses of cells. They carry out a process called cellular respiration, which has several steps:

* Glycolysis: This initial step happens in the cytoplasm (not the mitochondria) and breaks down glucose into pyruvate.

* Krebs Cycle (Citric Acid Cycle): This cycle takes place in the mitochondria and further breaks down pyruvate, releasing some energy.

* Electron Transport Chain: This final step also occurs in the mitochondria and is where oxygen plays a crucial role.

* Oxygen's Role: Oxygen is the final electron acceptor in the electron transport chain. As electrons move through the chain, they release energy used to create a proton gradient. This gradient drives the production of ATP (adenosine triphosphate), the cell's primary energy currency.

In summary, while organelles don't directly "use" oxygen, the mitochondria require oxygen as a key component in the process of cellular respiration to efficiently release energy from glucose.