By Sean Farmer • Updated Aug 30, 2022

Urea (NH₂₂CO) is an organic compound first isolated by Friedrich Wöhler in 1828. It is ubiquitous in the urine of animals and humans, and its high solubility in water makes it ideal for eliminating excess nitrogen from the body.

Step 1 – Weigh the Urea

Use a calibrated analytical balance to determine the exact mass of urea you intend to dissolve. Record this value, as it will guide the volume of water needed.

Step 2 – Measure the Water

Fill a graduated cylinder with a volume of water equal in mass to the urea sample. Matching masses ensures the solution remains concentrated enough to dissolve the compound without being overly diluted.

Step 3 – Combine and Stir

Pour the measured water into the cylinder, add the urea, and gently stir until the crystals are fully dissolved. A magnetic stirrer or manual stirring rod can accelerate dissolution.

Materials Required

• Analytical balance (scale)
• Graduated cylinder