Here's how to determine the oxidation number of carbon in glucose (C₆H₁₂O₆):

1. Assign Oxidation Numbers to Oxygen and Hydrogen:

* Oxygen: Usually has an oxidation number of -2, except in peroxides.

* Hydrogen: Usually has an oxidation number of +1, except in metal hydrides.

2. Set Up an Equation:

Since glucose is a neutral molecule, the sum of the oxidation numbers of all atoms must equal zero. Let "x" represent the oxidation number of carbon.

6x + 12(+1) + 6(-2) = 0

3. Solve for "x":

6x + 12 - 12 = 0

6x = 0

x = 0

Therefore, the oxidation number of carbon in glucose is 0.