* DNA (Deoxyribonucleic acid): This is the genetic material itself, containing the instructions for building and maintaining an organism. It's a long, complex molecule shaped like a double helix.
* Proteins: These play a crucial role in organizing and packaging the DNA. Histones are the most important proteins in this context, acting like spools around which the DNA is wound. This compacting process is necessary for the DNA to fit within the nucleus of a cell.
So, a chromosome is essentially a tightly wound package of DNA and proteins.