Sc₂O₃, scandium oxide, is an amphoteric oxide. This means it can react with both acids and bases.

Reaction with Acids:

* Sc₂O₃ reacts with acids to form scandium salts and water. For example:

```

Sc₂O₃ + 6HCl → 2ScCl₃ + 3H₂O

```

Reaction with Bases:

* Sc₂O₃ reacts with strong bases to form scandium(III) hydroxides. For example:

```

Sc₂O₃ + 6NaOH → 2Na₃[Sc(OH)₆]

```

Conclusion:

Therefore, Sc₂O₃ will react in both acidic and basic solutions.

Note: The reaction with bases is less common and typically occurs with strong bases like NaOH.