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  • Dehydration Synthesis: Building Macromolecules Like Proteins & Starch
    The chemical reaction used to synthesize macromolecules like polypeptides and starch is dehydration synthesis.

    Dehydration synthesis is a chemical reaction where a molecule of water is removed from two monomers, joining them together to form a larger polymer.

    Here's how it works:

    * Polypeptides: Amino acids are joined together by peptide bonds, formed through dehydration synthesis. The hydroxyl group (-OH) from one amino acid and a hydrogen atom (-H) from another are removed, forming a molecule of water and leaving a covalent bond between the two amino acids.

    * Starch: Glucose monomers are joined together by glycosidic bonds, also formed through dehydration synthesis. The hydroxyl group (-OH) from one glucose molecule and a hydrogen atom (-H) from another are removed, forming water and leaving a covalent bond between the two glucose molecules.

    Key features of dehydration synthesis:

    * Water is removed: This is the defining characteristic of dehydration synthesis.

    * Monomers join to form polymers: Small subunits (monomers) are linked together to create larger molecules (polymers).

    * Energy is required: Dehydration synthesis is an endergonic reaction, meaning it requires energy input.

    Example:

    In the synthesis of a polypeptide, two amino acids, glycine (Gly) and alanine (Ala), are joined together:

    * Glycine + Alanine -> Gly-Ala + H₂O

    Here, the removal of a water molecule allows the formation of a peptide bond between glycine and alanine, creating a dipeptide.

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