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  • Glycolysis: The 10 Steps to Breaking Down Glucose
    It takes 10 chemical steps to split a glucose molecule into two pyruvic acid molecules. This process is known as glycolysis.

    Here's a breakdown:

    1. Glucose is phosphorylated by ATP to form glucose-6-phosphate.

    2. Glucose-6-phosphate is isomerized to fructose-6-phosphate.

    3. Fructose-6-phosphate is phosphorylated by ATP to form fructose-1,6-bisphosphate.

    4. Fructose-1,6-bisphosphate is cleaved into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate.

    5. Dihydroxyacetone phosphate is isomerized to glyceraldehyde-3-phosphate.

    6. Glyceraldehyde-3-phosphate is oxidized and phosphorylated to 1,3-bisphosphoglycerate.

    7. 1,3-bisphosphoglycerate transfers a phosphate group to ADP, forming 3-phosphoglycerate and ATP.

    8. 3-phosphoglycerate is isomerized to 2-phosphoglycerate.

    9. 2-phosphoglycerate is dehydrated to phosphoenolpyruvate.

    10. Phosphoenolpyruvate transfers a phosphate group to ADP, forming pyruvate and ATP.

    Therefore, it takes 10 distinct chemical reactions or steps to break down one glucose molecule into two pyruvic acid molecules.

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