In a medical context:
* Cyst: A sac-like structure filled with fluid or semi-solid material, often containing debris or cells. These can occur in various parts of the body, like the skin, ovaries, kidneys, etc.
* Abscess: A collection of pus, which is a thick, semi-solid fluid containing dead white blood cells, bacteria, and other cellular debris. Abscesses can form in response to infection.
* Tumor: A mass of tissue that can be solid or contain semi-solid components. These can be benign or malignant.
In a geological context:
* Nodule: A rounded mass of mineral matter within another rock. It can be solid or contain semi-solid material, depending on its composition.
* Concretion: A hard, rounded mass formed by the precipitation of minerals around a nucleus. They can be solid or have semi-solid interiors.
Other possibilities:
* Fibroid: A noncancerous tumor found in the uterus. These can contain semi-solid tissue.
* Goiter: An enlargement of the thyroid gland, often containing nodules that can be solid or semi-solid.
To help narrow down the answer, please provide more context:
* Where is the nodule located? (Body part, geological formation, etc.)
* What is the surrounding tissue or material?
* What is the size and shape of the nodule?
* What is the consistency of the semi-solid material? (Fluid-like, pasty, etc.)
With more information, I can give you a more specific answer.