It seems you're asking about the disadvantages of cream peroxide, which is likely referring to hydrogen peroxide cream. It's important to understand that hydrogen peroxide is a powerful oxidizing agent and should be used with caution.

Here are some potential disadvantages:

* Skin irritation and allergic reactions: Hydrogen peroxide can irritate the skin, causing redness, itching, and dryness. Some people are allergic to it.

* Bleaching: It can bleach fabrics and hair, so be careful not to get it on clothes or hair.

* Not for open wounds: Hydrogen peroxide is not recommended for open wounds, as it can damage healthy tissue and delay healing.

* Potential for toxicity: High concentrations of hydrogen peroxide can be toxic if ingested.

* Not a cure-all: While sometimes used for minor skin infections, it's not a replacement for proper medical care.

It's important to consult a doctor or pharmacist before using hydrogen peroxide cream, especially if you have sensitive skin, allergies, or any underlying health conditions.

If you're concerned about a specific skin condition, it's best to seek professional medical advice. They can diagnose the issue and recommend the most appropriate treatment.