Here's the breakdown:
1. PIP2 is a phospholipid located in the cell membrane.
2. PLC is activated by various signaling molecules like hormones, neurotransmitters, and growth factors.
3. Activated PLC cleaves PIP2 into two products:
* Diacylglycerol (DAG): This remains embedded in the cell membrane.
* Inositol trisphosphate (IP3): This diffuses into the cytoplasm.
So, DAG is a direct product of PIP2 hydrolysis by PLC.