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  • 20 Antimicrobial Molecules: Types, Mechanisms & Examples

    20 Different Types of Antimicrobial Molecules:

    1. Antibiotics:

    * Penicillins: Inhibit bacterial cell wall synthesis (e.g., penicillin G, amoxicillin)

    * Cephalosporins: Inhibit bacterial cell wall synthesis (e.g., cefazolin, ceftriaxone)

    * Macrolides: Inhibit bacterial protein synthesis (e.g., erythromycin, azithromycin)

    * Tetracyclines: Inhibit bacterial protein synthesis (e.g., tetracycline, doxycycline)

    * Aminoglycosides: Inhibit bacterial protein synthesis (e.g., gentamicin, tobramycin)

    * Fluoroquinolones: Inhibit bacterial DNA replication (e.g., ciprofloxacin, levofloxacin)

    2. Antifungal Agents:

    * Azoles: Inhibit fungal ergosterol synthesis (e.g., fluconazole, ketoconazole)

    * Polyenes: Bind to fungal cell membranes (e.g., amphotericin B, nystatin)

    * Echinocandins: Inhibit fungal cell wall synthesis (e.g., caspofungin, micafungin)

    3. Antiviral Agents:

    * Nucleoside Analogs: Inhibit viral DNA or RNA synthesis (e.g., acyclovir, oseltamivir)

    * Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs): Inhibit HIV reverse transcriptase (e.g., efavirenz, nevirapine)

    * Protease Inhibitors: Inhibit viral protease activity (e.g., ritonavir, indinavir)

    4. Antiparasitic Agents:

    * Antimalarials: Inhibit parasite growth and development (e.g., chloroquine, artemisinin)

    * Antiprotozoals: Target different stages of parasite life cycles (e.g., metronidazole, albendazole)

    5. Other Antimicrobial Molecules:

    * Iodine: Oxidizes and damages bacterial cell membranes

    * Chlorhexidine: Disrupts bacterial cell membranes

    * Hydrogen Peroxide: Produces reactive oxygen species that damage bacterial cells

    * Silver: Interferes with bacterial enzyme function

    * Alcohol (Ethanol and Isopropanol): Denatures bacterial proteins

    * Phenolics: Disrupt bacterial cell membranes

    * Quaternary Ammonium Compounds: Disrupt bacterial cell membranes

    * Bismuth Subsalicylate: Inhibits bacterial adherence and toxin production

    Note: This is not an exhaustive list, and there are many other antimicrobial molecules with diverse mechanisms of action. The development of new antimicrobials is ongoing, and new classes of molecules are constantly being discovered.

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