An amine and a carboxylic acid react to form water and an amide.

This reaction is called amide formation or amidation.

Here's a simplified representation:

* Amine (R-NH2) + Carboxylic acid (R'-COOH) → Amide (R-CO-NH-R') + Water (H2O)

Example:

* Methylamine (CH3NH2) + Acetic acid (CH3COOH) → N-methylacetamide (CH3CONHCH3) + Water (H2O)

This reaction is an equilibrium reaction. The formation of the amide is favored when water is removed from the reaction mixture.