Here's what it means:

* ISO stands for the International Organization for Standardization. It is a global organization that sets standards for various industries.

* Non-Conformance is a deviation from a specified requirement. In the context of ISO, it refers to a situation where a product, process, or system does not meet the requirements of a relevant ISO standard.

Example: A factory producing medical devices might be issued an NC if their production process does not meet the requirements of ISO 13485, which specifies quality management systems for medical devices.