Zinc oxide is not an effective treatment for mange. Mange is caused by mites that burrow under the skin, leading to intense itching and skin lesions. Zinc oxide, on the other hand, is typically used as a mild antiseptic or sunblock and does not have the necessary properties to kill or repel the mites responsible for mange.

Appropriate treatments for mange usually involve miticides or parasiticides specifically formulated for the type of mites causing the condition. Consulting a veterinarian to diagnose the exact cause of the skin problem and obtain the appropriate medication is crucial for effectively treating mange.