Neon, argon, and helium are all noble gases, which means they are the least reactive elements on the periodic table. They have full valence shells, which means their outer electron shells are full and they do not need to react with other elements to obtain a more stable configuration. Helium, with two protons and two electrons, has the most stable nucleus among the three.

Therefore, among these three elements, there isn't any most reactive element as they are inert and display minimal chemical reactivity.