The best liquid to remove iodine stains is a solution of sodium thiosulfate. This chemical is commonly used in photography to neutralize the effects of fixer, which contains iodine. To use sodium thiosulfate to remove an iodine stain, make a 5% solution by dissolving 5 grams of sodium thiosulfate in 100 milliliters of water. Apply the solution to the stain and let it sit for a few minutes before rinsing it off with water. Sodium thiosulfate is safe for use on most fabrics and surfaces, but it is always a good idea to test it on a small area before using it on a larger scale.