For example, if a radioactive substance has a half-life of 1 hour, then after 1 hour, half of the radioactive atoms in the substance will have decayed. After another 1 hour, half of the remaining radioactive atoms will have decayed, and so on.
The half-life of a radioactive substance is used to determine how long it will take for the substance to become safe to handle. For example, if a radioactive substance has a half-life of 100 years, then it will take 100 years for the substance to decay to a level that is safe to handle.