Here's a breakdown of the process and why you might see the number 34 mentioned:
* Glycolysis: This initial step occurs in the cytoplasm and breaks down glucose into pyruvate, producing 2 ATP molecules and 2 NADH molecules.
* Krebs Cycle (Citric Acid Cycle): This occurs in the mitochondria and further breaks down pyruvate, producing 2 ATP, 6 NADH, and 2 FADH2 molecules per glucose molecule.
* Oxidative Phosphorylation: This is the final stage, where the electron transport chain uses the NADH and FADH2 from the previous stages to generate a proton gradient across the mitochondrial membrane. This gradient is then used by ATP synthase to produce ATP.
Here's where the "34 ATP" number comes from:
* Theoretical Maximum: Theoretically, each NADH molecule can generate 3 ATP molecules, and each FADH2 molecule can generate 2 ATP molecules. If we add up all the NADH and FADH2 produced during glycolysis, the Krebs cycle, and oxidative phosphorylation, we get a total of 10 NADH and 2 FADH2 molecules per glucose molecule. This would yield a theoretical maximum of 34 ATP (10 NADH x 3 ATP + 2 FADH2 x 2 ATP = 34 ATP).
However, this is not entirely accurate:
* Efficiency Loss: The actual ATP yield is lower than the theoretical maximum. Some energy is lost as heat during the process.
* Variable Factors: The exact number of ATP produced can vary depending on factors like the type of cell, the shuttle system used for transporting electrons, and the efficiency of the electron transport chain.
In summary: While the number 34 ATP is often cited, it's a theoretical maximum that doesn't fully reflect the real-world efficiency of cellular respiration. The actual ATP yield per glucose molecule is closer to 29-32.