1. Cyclins: These are proteins that fluctuate in concentration throughout the cell cycle. They act as activators of cyclin-dependent kinases (CDKs).
2. Cyclin-dependent kinases (CDKs): These are protein kinases that are activated by binding to cyclins. Once activated, CDKs phosphorylate various target proteins, initiating and regulating the different stages of the cell cycle.
It's important to note that these two types of regulators work in concert. Cyclins act as the "on" switch for CDKs, and CDKs are the "doers" that drive the cell cycle forward.
Here's a simplified analogy: Imagine the cell cycle as a car. Cyclins are like the keys that turn on the engine (CDKs), and CDKs are the engine itself that propels the car (cell) forward.
Let me know if you would like a more detailed explanation of how cyclins and CDKs interact or the specific stages of the cell cycle they control!