While all three scientists played pivotal roles in deciphering the genetic code, Nirenberg and Khorana are often specifically credited with its elucidation. Nirenberg was the first to break the code, demonstrating the role of specific codons in determining specific amino acids. Khorana, on the other hand, developed methods for synthesizing specific DNA sequences, which helped further validate Nirenberg's findings and ultimately led to the complete deciphering of the genetic code.