The type of cell that has a nucleus and a large vacuole is a plant cell.

Here's why:

* Nucleus: Both plant and animal cells have a nucleus, which contains the cell's genetic material (DNA).

* Large Vacuole: Plant cells are characterized by having a large central vacuole that takes up most of the cell's volume. This vacuole plays a crucial role in maintaining cell turgor (rigidity), storing water, nutrients, and waste products.

Animal cells also have vacuoles, but they are much smaller and less prominent than the large central vacuole found in plant cells.