The organelles composed of RNA and protein in the cytoplasm that aid in protein manufacture are ribosomes.

Here's why:

* Ribosomes are the protein synthesis machinery: They read the genetic code carried by messenger RNA (mRNA) and use that information to assemble amino acids into proteins.

* RNA and protein composition: Ribosomes are composed of ribosomal RNA (rRNA) and proteins. The rRNA provides the structural framework, while the proteins are involved in various functions like binding mRNA and tRNA, facilitating peptide bond formation, and ensuring accurate translation.

Let me know if you'd like to learn more about the specific roles of RNA and protein in ribosomes or the process of protein synthesis!