This is a bit of a trick question! All human cells, with the exception of red blood cells, do have chromosomes.

Here's why:

* Red blood cells (erythrocytes) lose their nucleus during development. This is to maximize space for carrying oxygen. Since the nucleus houses the chromosomes, mature red blood cells lack them.

* All other human cells (e.g., skin cells, muscle cells, nerve cells) have a nucleus and therefore chromosomes. These chromosomes carry the genetic information that determines the cell's function and characteristics.

Let me know if you have any other questions!