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  • Chromatin: How DNA Folds to Fit Inside the Nucleus
    The structure that allows enormous lengths of DNA to be folded inside the nucleus is called chromatin.

    Here's how it works:

    * DNA itself is a very long, thin molecule. If it were simply stretched out, it would be much longer than the nucleus itself.

    * Histones are proteins that DNA wraps around, like thread around a spool. This creates a structure called a nucleosome.

    * Nucleosomes are then further folded and compacted into a 30 nm fiber.

    * This 30 nm fiber is then organized into loops and domains, eventually forming the chromosomes that we see during cell division.

    This intricate folding process allows for the efficient packaging of DNA within the nucleus, preventing tangling and allowing for the regulation of gene expression.

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