The specificity of enzymes refers to their ability to catalyze only a specific reaction or a very small number of reactions involving specific molecules called substrates. This is due to the unique three-dimensional structure of the enzyme, which creates a specific active site that complements the shape and chemical properties of the substrate.

Here are some statements that describe this:

* Enzymes are highly selective in their choice of substrates. They only interact with and catalyze reactions involving specific molecules.

* The active site of an enzyme is complementary to the substrate. This means the shape and chemical environment of the active site match the substrate, allowing for a precise interaction.

* Enzymes are like locks and keys. The substrate is the key that fits into the lock (active site) of the enzyme.

* Specificity is a result of the enzyme's unique three-dimensional structure. This structure is determined by the sequence of amino acids in the enzyme.

Let me know if you'd like more details on specific types of enzyme specificity!