DNA changes to RNA in the nucleus of the cell, specifically at a region called the chromatin. Here's a breakdown:

* DNA resides within the nucleus, organized into structures called chromosomes.

* Chromatin is the complex of DNA and proteins that make up chromosomes.

* Transcription is the process where DNA is copied into RNA.

* RNA polymerase is the enzyme responsible for transcription. It binds to specific regions of DNA called promoters, unwinds the DNA, and uses one strand as a template to create a complementary RNA molecule.

This RNA molecule, called messenger RNA (mRNA), then travels out of the nucleus to the cytoplasm, where it's used to make proteins.