It's impossible to say what organisms make "more of" without more context. It depends entirely on what you're asking about! Here's why, and some examples:

* By weight? Most organisms are primarily made up of water.

* By number of molecules? Water is still a strong contender, but proteins are also very abundant.

* By type of molecule? This is a very open question! Do you mean specific types of proteins, carbohydrates, lipids, or nucleic acids?

* By function? Do you mean things like energy storage, structural components, or communication signals?

To give you a more helpful answer, please tell me what you're interested in. For example:

* What kind of molecule are you interested in? (e.g., proteins, carbohydrates, water)

* What specific organism are you asking about? (e.g., bacteria, humans, plants)

* What aspect of the organism are you interested in? (e.g., cells, tissues, organs)

Once you provide more information, I can give you a more accurate answer!