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  • Cellular Respiration: Where Does It Occur? - Cytoplasm & Mitochondria
    Cellular respiration happens in multiple parts of the cell, specifically:

    * Cytoplasm: The first stage of cellular respiration, glycolysis, occurs in the cytoplasm.

    * Mitochondria: The remaining stages of cellular respiration, the Krebs cycle and oxidative phosphorylation, take place in the mitochondria.

    Let me break it down further:

    * Glycolysis: This process breaks down glucose into pyruvate, generating a small amount of ATP and NADH.

    * Krebs cycle (Citric Acid Cycle): This cycle occurs in the mitochondrial matrix and further breaks down pyruvate to release CO2 and generate more ATP, NADH, and FADH2.

    * Oxidative Phosphorylation: This final stage occurs in the inner mitochondrial membrane and uses the electron carriers NADH and FADH2 to create a proton gradient across the membrane. This gradient is then used to drive ATP production.

    So, while the mitochondria is often referred to as the "powerhouse of the cell", the entire process of cellular respiration involves multiple compartments within the cell.

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