Here's why:

* High energy demand: Neurons are highly active cells that require a constant supply of ATP to maintain their electrical gradients, transmit signals, and perform other essential functions.

* Oxygen dependence: Aerobic respiration, which uses oxygen, is far more efficient at producing ATP than anaerobic respiration.

* Limited anaerobic capacity: While neurons can use anaerobic respiration for a short period, they are highly susceptible to damage from prolonged oxygen deprivation.

Therefore, neurons rely heavily on a continuous supply of oxygen to maintain their energy needs.