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  • Understanding Aneuploidy: Definition & Significance in Somatic Cells
    A somatic cell that does not contain a multiple of 23 chromosomes is called aneuploid.

    Here's why:

    * Somatic cells are any biological cells forming the body of a multicellular organism other than gametes, germ cells, gametocytes or undifferentiated stem cells.

    * Normal human somatic cells are diploid, meaning they contain two sets of chromosomes (2n), for a total of 46 chromosomes. Each set has 23 chromosomes.

    * Aneuploidy is a condition in which the number of chromosomes in a cell is not a multiple of the normal haploid number (23 for humans). This can happen due to errors during cell division, such as non-disjunction.

    Examples of aneuploid conditions include:

    * Trisomy 21 (Down syndrome): Individuals have an extra copy of chromosome 21 (47 total chromosomes).

    * Monosomy X (Turner syndrome): Individuals have only one X chromosome (45 total chromosomes).

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