That statement is not entirely accurate. While enzymes do not make up the majority of cellular mass, they are not a small minority either.

Here's why:

* Enzymes are diverse: There are thousands of different enzymes in a cell, each with a specific function.

* Important for metabolism: Enzymes are essential for nearly all metabolic processes, including breaking down nutrients, building molecules, and generating energy.

* Varying concentrations: The concentration of different enzymes varies depending on the cell type and its function.

* Not the only proteins: While many enzymes are proteins, there are also some RNA-based enzymes (ribozymes).

So, while enzymes might not be the most abundant component of cellular mass, their significance in biological processes is substantial.

In summary:

* Enzymes are vital for cellular function but do not make up the majority of cellular mass.

* They represent a significant portion of cellular proteins, and their concentration can vary greatly between cell types.