Here's a breakdown of how they work:
* T cell receptors (TCRs): T cells have specialized receptors on their surface called TCRs. These receptors recognize specific antigens, which are molecules on the surface of other cells that can trigger an immune response.
* Antigen presentation: Antigens are presented to T cells by other immune cells, like macrophages and dendritic cells, which have engulfed and processed the antigens.
* Activation: When a T cell's TCR binds to its specific antigen, it becomes activated.
* T cell differentiation: Activated T cells differentiate into different types, each with a specific function:
* Cytotoxic T cells (CD8+ T cells): These cells directly kill infected or cancerous cells by releasing cytotoxic molecules.
* Helper T cells (CD4+ T cells): These cells help activate other immune cells, including B cells, which produce antibodies.
Key point: T cells are a crucial part of the adaptive immune system, which allows the body to recognize and destroy specific pathogens or cancer cells.