The cell organelle responsible for powering the cell is the mitochondrion.

Here's why:

* Energy Production: Mitochondria are the sites of cellular respiration, a process that breaks down glucose (sugar) to produce ATP (adenosine triphosphate). ATP is the main energy currency of cells, used to fuel all cellular activities.

* Powerhouse of the Cell: The nickname "powerhouse of the cell" aptly describes the mitochondrion's crucial role in energy production.

While other organelles like chloroplasts (in plant cells) also play a role in energy production, the mitochondrion is the primary source of energy for most cells.