Nucleic acids themselves are macromolecules. They are not made up of other macromolecules.

However, nucleic acids are made up of smaller subunits called nucleotides. Each nucleotide consists of three parts:

* A sugar: Either ribose (in RNA) or deoxyribose (in DNA)

* A phosphate group: A molecule containing phosphorus and oxygen

* A nitrogenous base: One of five different molecules containing nitrogen, which are adenine (A), guanine (G), cytosine (C), thymine (T) (in DNA), or uracil (U) (in RNA)

These nucleotides are linked together in long chains to form the nucleic acid polymers.

So, while nucleic acids are macromolecules, they are not made up of other macromolecules. They are made up of smaller units called nucleotides.