Here's how it works:
* ADH is released from the pituitary gland in response to dehydration.
* It travels to the kidneys and binds to receptors on the collecting ducts of the nephrons.
* This binding triggers the insertion of aquaporins (water channels) into the cell membranes of the collecting duct cells.
* Aquaporins allow water to move more freely from the filtrate back into the bloodstream, leading to increased water reabsorption and concentrated urine.
Therefore, ADH helps prevent water loss, not retention.
